Anti-Insulin (INS) Antibody ELISA Kit

Short Description:

This kit is used for the qualitative in vitro detection of anti-insulin antibodies in human serum.

In normal populations, the presence of insulin antibodies in the blood makes them prone to developing Type 1 Diabetes Mellitus (T1DM). Anti-insulin antibodies may be produced due to β-cell damage, so their detection can serve as a marker of autoimmune β-cell injury. They are also the first immune markers to appear in children at high risk of T1DM, and can be used for the early detection and prevention of T1DM, as well as providing certain guidance for the diagnosis and prognosis of T1DM.

The presence of insulin antibodies in the blood is an important cause of insulin resistance. Diabetic patients receiving insulin therapy may develop insulin resistance due to the production of insulin antibodies, characterized by increasing insulin dosage but unsatisfactory blood glucose control. At this time, insulin antibodies should be tested; positive results or increased titers can serve as objective evidence of insulin resistance. Additionally, this detection plays an auxiliary role in the diagnosis of Insulin Autoimmune Syndrome (IAS).